The idea behind OSD in Configuration Manager is automation. Right? We want to create a process to eliminate as many manual tasks as possible. Some companies have their technicians manually disable IPv6 on all adapters. Who wants to do all of that manual work when we can have it automated? My clients occasionally ask for a step in the OSD Task Sequence to disable IPv6. If you would like to disable IPv6 on all interfaces, you should do it in a way that is easily reversible on your client computers companywide. Here is how I did this for a recent client:
Unselect IPv6 from the properties of your NIC.
Under the regkey HKLM\SYSTEM\CurrentControlSet\Services\Tcpip6\Parameters, add a 32 bit DWORD with the name DisabledComponents and value 0xFFFFFFFF.
Reboot the machine.