Remove a PHY NIC from an UpLink in a vDS at the command line:
esxcfg-vswitch --list : Create a listing needed to get the reference for a vmnic's PortID#.
esxcfg-vswitch -V <vmnics PortID#> -Q <vmnic> <NAME of virtual Distributed Switch as it appears in vCenter inventory>
# esxcfg-vswitch -V 577 -Q vmnic1 NET2-N1K-VDS
Delete a Physical NIC from a standard virtual Switch on a Host: